This report offers insights on pathogenic/likely pathogenic variants found within the set of 59 core health genes as recommended by the American College of Medical Genetics and Genomics (ACMG). The ACMG 59 test can reveal three types of conditions: cancer predispositions, cardiovascular predispositions, and metabolic conditions. While most of these conditions are inherited, In all three cases, knowing about these conditions ahead of time can give you the power to make informed decisions and potentially avoid health complications